PIP5K1B Polyclonal Antibody Store at -20C
| SKU # | E-AB-10952 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PIP5K1B |
| Abbre | PIP5K1B |
| Synonyms | MSS 4,MSS4,PI4P5K 1 beta,PI51B,PIP5K1-beta,PIP5K1B,PIP5KIbeta,Phosphatidylinositol 4 phosphate 5 kinase type 1 beta,Phosphatidylinositol-4-phosphate 5-kinase type I beta,Phosphatidylinositol-4-phosphate 5-kinase type-1 beta,Pipk 5 beta,Pipk 5b,Protein ST |
| Swissprot | O14986 |
| Cellular Localization | Endomembrane system. Associated with membranes. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization.The PIPK family is divided into type I, type II and type III .Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting .The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I , , and , which are characterized by phosphorylating PI4P on the 5-hydroxyl .PIPK I (designated PIPK I in mouse) is expressed in brain tissue .PIPK I , designated PIPK I a in mouse, is also called STM7.PIPK I has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.
